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Research

Some key research focussing on the wide range of conditions in hypermobility and neurodivergence both physical and mental and neurodevelopmental

Is joint hypermobility linked to self reported non-recovery from COVID-19? COVID Symptom Study Biobank 2024 Jessica A Eccles, Dorina Cadar, Lisa Quadt, Alan J Hakim, Nicholas Gall; Covid Symptom Survey Biobank Consortium, Vicky Bowyer, Nathan Cheetham, Claire J Steves, Hugo D Critchle, Kevin A Davies This study sought to explore whether generalised joint hypermobility (GJH, a common marker of variant connective tissue) was a risk factor for self-reported non-recovery from COVID-19 infection. Read more.

Joint Hypermobility Links Neurodivergence to Dysautonomia and Pain Csecs JLL, Iodice V, Rae CL, Brooke A, Simmons R, Quadt L, Savage GK, Dowell NG, Prowse F, Themelis K, Mathias CJ, Critchley HD, Eccles JA. (2022) This paper found that adults diagnosed with neurodevelopmental conditions (Autistic, ADHD, Tourette syndrome, Dyspraxia) show significantly higher rates of joint hypermobility (hypermobility) a connective tissue variation than the general population and that hypermobility mediates the relationship between neurodivergence and increased symptoms of autonomic dysfunction and musculoskeletal pain

Co-Occurring Physical Health Challenges in Neurodivergent Children and Young People: A Topical Review and Recommendation Bethany Donagh, David Moore & Jane Green (2023) Neurodivergence has been established as associated with a significant number of co-occurring physical conditions, particularly for autistic individuals who are at risk for increased pain, hypermobility (including Ehlers-Danlos Syndrome) and gastrointestinal problems. However, data, so far, has been focused on adults and generally limited to discussions of condition prevalence alone. Education

Variant connective tissue (joint hypermobility) and its relevance to depression and anxiety in adolescents: a cohort-based case–control study (2022) Jessica A Eccles, Lisa Quadt, Hannah McCarthy, Kevin A Davies, Rod Bond, Anthony S David, Neil A Harrison, Hugo D Critchley. To test whether variant connective tissue structure, as indicated by the presence of joint hypermobility, poses a developmental risk for mood disorders in adolescence.

"I hear you". Validation in the context of children's pain as an untapped opportunity to prevent chronic pain (2024) Wallwork, Sarah B.; Shenk, Chadb,c; McMurtry, C. Meghand; Hood, Anna M.e; Pavlova, Mariaf; Olson, Anneke E.b; Moseley, G. Lorimera; Noel, Melanieg PAIN: The Journal of the International Association journal for the Study of Pain.​​

Nutritional Considerations for Hypermobile Ehlers-Danlos Syndrome (2024)Cheryl Iny Harris, Dacre R.T. Knight, Lisa A. Mejia, Laurie Bilyeu. While the hallmarks of hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorders (HSD) are pain, joint instability, and injuries to soft tissues, most patients with hEDS and HSD have a myriad of manifestations within the gastrointestinal tract that affect dietary tolerance and quality of life.

Maxwell-Scott, M., O’Keeffe, F., & Eccles, F. J. R. (2024). Coping with Tourette’s syndrome: a meta-ethnography of individual and family perspectives. Psychology & Health, 1–23. https://doi.org/10.1080/08870446.2024.2360126

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